Mastering CPT®, HCPCS, and E/M Modifiers: Accurate Reporting and Maximum Reimbursement in 2025

A practical, case-based deep dive into modifiers 24, 25, 57, 59, and beyond — what they mean, when to use them, and when not to.

Modifiers are small codes with big impact — the two-digit indicators that tell payors why a service should be paid separately, how it differs from another procedure, or when circumstances justify an exception. Yet, even seasoned coders and billers can struggle with their correct use. Improper modifier reporting continues to be one of the most common reasons for claim denials, audit findings, and compliance issues.

Join nationally recognized coding expert Lynn M. Anderanin for this comprehensive and practical session that will demystify the use of CPT®, HCPCS, and E/M modifiers. You’ll gain the clarity needed to confidently apply the right modifiers — every time — to protect revenue, ensure compliance, and minimize audit risks.

Why This Webinar Matters

Modifiers are not just coding details — they directly impact reimbursement and compliance. With ongoing updates to CMS policies, NCCI edits, and payer-specific rules, correct modifier use is more critical than ever in 2025.

This training will walk you through real-world case examples, coding decision scenarios, and documentation requirements to help you determine when modifiers such as -24, -25, -57, -59, 58, 78, 79, 22, 51, 52, and others should (or should not) be applied.

Whether you work in a physician’s office, billing service, ASC, or hospital setting, this session will strengthen your coding accuracy and reduce costly mistakes.

Webinar Objectives

By attending this session, participants will be able to:

• Differentiate between E/M, CPT®, and HCPCS modifiers and understand when each category applies.
• Apply Modifier 25 and 57 correctly in line with CMS and NCCI guidelines to ensure compliant reporting of same-day E/M services.
• Recognize global periods and postoperative billing rules, including when to report modifiers 24, 58, 78, and 79.
• Understand payer-specific nuances for modifiers 50 (bilateral), 51 (multiple procedures), and 52/53 (reduced or discontinued services).
• Identify “distinct procedural services” and use modifier 59 (and its X{E,P,S,U} subsets) accurately to bypass NCCI edits without triggering denials.
• Clarify documentation and claim requirements for anesthesia, body part, and professional/technical component modifiers (26 and TC).
• Avoid common pitfalls that lead to claim rejections, denials, or audits.

Webinar Highlights

• Overview of E/M Modifiers (24, 25, 57, 32)
• CPT® Modifiers: 22, 51, 52, 53, 59
• Medicare and NCCI Guidelines for Modifier 25
• Global Surgery Rules: Minor vs. Major Procedures
• Understanding Postoperative Periods and Repeat Procedures
• Medicare’s XE, XS, XP, XU Modifiers – When and How to Use Them
• Correct Application of 58, 78, and 79 Modifiers for Postoperative Services
• Bilateral, Body Part, and Professional/Technical Modifiers
• Radiology and Anesthesia Modifiers Explained
• Real-Life Case Studies: “Modifier 25 — Yes or No?”

Who Should Attend

Certified Professional Coders (CPCs), Medical Billing Specialists, Compliance Officers, Revenue Cycle Managers, Practice Administrators, Auditors, Physicians and Clinical Staff involved in documentation